Added: Martia Kear - Date: 01.01.2022 04:13 - Views: 46881 - Clicks: 8280
One of the original chemists who deed synthetic cannabis for research purposes, John W. New Hampshire has declared a state of emergencyand the of emergency room visits for overdose from the synthetic drug has jumped.
One teen died earlier this month after slipping into a coma, reportedly from using the drug. Synthetic cannabis, unlike pot, however, can cause a huge variety of symptomswhich can be severe: Agitation, vomiting, hallucination, paranoia, tremor, seizure, tachycardia, hypokalemia, chest pain, cardiac problems, stroke, kidney damage, acute psychosis, brain damage, and death.
Why are the effects of synthetic cannabis so varied and so toxic? Researchers are starting to understand more about the drugs, and finding that synthetic cannabis is not even close to being the same drug as pot. Its name, which is utterly misleading, is where the similarity ends. One reason that synthetic cannabis can trigger everything from seizures to psychosis is how it acts in the brain. But when it binds, it acts as a full agonistrather than a partial agonist, meaning that it can activate a CB 1 receptor on a brain cell with maximum efficacy, rather than only partially, as with THC.
I drink gallons of it in some college contest, and I could have a seizure and die.
Synthetic cannabinoids are tailor-made to hit cannabinoid receptors — and hit it hard. This is NOT marijuana. Its action in the brain may be similar but the physical effect is so different. Another issue with synthetic is its potency, which huge. So these things have higher efficacy and potency…These things are clearly very different from THC and thus not surprising that their use may result in development of life-threatening adverse effects.
A central reason that synthetic cannabis can produce such an enormous variety of side effects is likely because CB 1 receptors are present in just about every brain region there is. And in the prefrontal cortex, this is probably why you see stronger psychosis with synthetic cannabinoids.
It might be any one of these that produces the greatest risk of death. Everyone once in a while we see a bad trip with natural marijuana. But it goes away quickly. One possibility is that the metabolites of synthetic cannabis are also doing damage to the brain. Usually our bodies deactivate a drug as it metabolizes it, but this may not be the case with synthetic.
The synthetic metabolites seem to retain full activity relative to the parent compound. So the ability of our bodies to deactivate them may be decreased. Synthetic cannabis is made in underground labs, often in China, and probably elsewhere. The makers take some random herb, and spray it with cannabinoid. How MUCH synthetic cannabis is in there? There are hundreds of different forms of JWH, and of other synthetic cannabinoids deed by different labs, and the next one is always waiting to go.
It took months for the local authorities to figure out what was in it and regulate it. The next week incense blends with another compound, JWH, came out. First we created black market by making marijuana illegal. Then there are all these loopholes in the legislation, so you can feed synthetics through when you change one molecule and call it a different drug.
His solution is a three-pronged: Changing the laws, by moving form a rule-based to a standards-based system, is the first step. There will always be a loophole. So you have to move to standards-base. We really need good deer drug legislation reform. The second step is that get the public health message across that synthetic cannabinoids can kill. Let parents know, let kids know — this is not the same thing.
You are experimenting with unknown compounds. Medically, these drugs are a world of difference from THC. The last step, he says, is to continue the legalization discussion. Some states are leading the way. We know people are going to use it. No athlete, soldier, student, or parolee wants to test positive for THC. Whether legalization of natural marijuana is the solution isn't totally clear. But remind your friends or kids that being a human subject in an uncontrolled synthetic drug experiment is just stupid. This is not marijuana.
It should not be thought of like marijuana. We have to get this out there: Its effects are serious. I fell into writing about health shortly after grad school, where I realized I didn't want to work in a lab for the rest of my life!
My main areas of interest are the…. My main areas of interest are the brain and behavior, as well as what influences the decisions we make about our health, and how we can change it over time. My work appears in other publications, including the magazine of the University of Chicago's Business School, YogaGlo.
Please me at alicegwalton [at] gmail [dot] com or visit my website www. This is a BETA experience. You may opt-out by clicking here. Jul 24,pm EDT. Jul 10,am EDT. Jul 9,am EDT. Jul 7,pm EDT. Jul 6,pm EDT. Edit Story.
Aug 28,am EDT. Alice G. Half a gram of JWH Follow me on Twitter or LinkedIn. My main areas of interest are the… .Skunk synthetic weed
email: [email protected] - phone:(667) 237-3962 x 7259
What Does Spice Look Like?